Maximilian Kueckelhaus, M.D., Tobias Rothoeft, M.D., Laura De Rosa, Ph.D., Burcu Yeni, B.Sc., Tobias Ohmann, Ph.D., Christoph Maier, M.D., Lynn Eitner, M.D., Dieter Metze, M.D., Lorena Losi, M.D., Ph.D., Alessia Secone Seconetti, Ph.D., Michele De Luca, M.D., and Tobias Hirsch,…
Enzo E, Secone Seconetti A, Forcato M, Tenedini E, Polito MP, Sala I, Carulli S, Contin R, Peano C, Tagliafico E, Bicciato S, Bondanza S, De Luca M. ABSTRACT Autologous epidermal cultures restore a functional epidermis on burned patients. Transgenic…
Front Bioeng Biotechnol . 2021 Mar 25;9:652214. doi: 10.3389/fbioe.2021.652214. eCollection 2021. Regenerative Medicine of Epithelia: Lessons From the Past and Future Goals Maurizi E, Adamo D, Magrelli FA, Galaverni G, Attico E, Merra A, Maffezzoni MBR, Losi L, Genna VG,…
Maurizi E, Schiroli D, Zini R, Limongelli A, Mistò R, Macaluso C, Pellegrini G. ABSTRACT Corneal endothelial (CE) dysfunction is the main indication for corneal transplantation, an invasive procedure with several limitations. Developing novel strategies to re-activate CE regenerative capacity…
Sci Rep. 2020 Aug 14;10(1):13841. doi: 10.1038/s41598-020-70800-w. Surgery Versus ATMPs: An Example From Ophthalmology Magrelli Federica M, Merra A., Pellegrini G. Abstract Advanced therapy medicinal products (ATMPs) are the new frontier of medicine. Advanced therapy medicinal products are set out to…
Cell Prolif. 2019 Nov;52(6):e12653. doi: 10.1111/cpr.12653. Epub 2019 Sep 6. Bioreactor-manufactured cartilage grafts repair acute and chronic osteochondral defects in large animal studies ukasovic A, Asnaghi MA, Kostesic P, Quasnichka H, Cozzolino C, Pusic M, Hails L, Trainor N, Krause C,…
World J Urol. 2019 Jul 9. doi: 10.1007/s00345-019-02864-x. [Epub ahead of print] Preclinical study for treatment of hypospadias by advanced therapy medicinal products. Sceberras V, Attico E, Bianchi E, Galaverni G, Melonari M, Corradini F, Fantacci M, Ribbene A, Losi…
De Luca M, Aiuti A, Cossu G, Parmar M, Pellegrini G, Robey PG ABSTRACT Despite many reports of putative stem-cell-based treatments in genetic and degenerative disorders or severe injuries, the number of proven stem cell therapies has remained small. In…
Cell Rep. 2019 May 14;27(7):2036-2049.e6. doi: 10.1016/j.celrep.2019.04.055. Laminin 332-Dependent YAP Dysregulation Depletes Epidermal Stem Cells in Junctional Epidermolysis Bullosa De Rosa L, Secone Seconetti A, De Santis G, Pellacani G, Hirsch T, Rothoeft T, Teig N, Pellegrini G, Bauer JW, De Luca M ABSTRACT Laminin 332-deficient junctional epidermolysis bullosa (JEB) is…
Cornea. 2019 Mar;38(3):364-375. doi: 10.1097/ICO.0000000000001820. Global Consensus on Definition, Classification, Diagnosis, and Staging of Limbal Stem Cell Deficiency Deng SX, Borderie V, Chan CC, Dana R, Figueiredo FC, Gomes JAP, Pellegrini G, Shimmura S, Kruse FE; and The International Limbal Stem Cell…
