Holostem is the first biotechnological company entirely devoted to development, manufacture, registration and distribution of Advanced Therapies Medicinal Products (ATMPs) based on cultures of epithelial stem cells both for cell and gene therapy.

STEM
CELLS

CELL
THERAPY

GENE
THERAPY

TECHNOLOGY

Holostem Terapie Avanzate is located into the Centre for Regenerative Medicine “Stefano Ferrari” of the University of Modena and Reggio Emilia.

Newcastle pharmacy experts work with Italian biotech lab to provide access to sight-saving treatment across England

News

9 months ago

June 24, 2022 – A life-changing treatment to reverse injury-related sight loss is now available to patients at specialist centres across England, thanks to a partnership between Newcastle Hospitals and…

Holostem Terapie Avanzate begins its transition to a Foundation

News

10 months ago

The board of directors unanimously approved the company’s evolution into a nonprofit organization Holostem will remain an international point of reference for patients and research Modena, 1st of June 2022…

Transgenic Epidermal Cultures for Junctional Epidermolysis Bullosa — 5-Year Outcomes

Publications

1 year ago

Maximilian Kueckelhaus, M.D., Tobias Rothoeft, M.D., Laura De Rosa, Ph.D., Burcu Yeni, B.Sc., Tobias Ohmann, Ph.D., Christoph Maier, M.D., Lynn Eitner, M.D., Dieter Metze, M.D., Lorena Losi, M.D., Ph.D., Alessia…

Gene therapy for butterfly children: 5-year follow-up published in the New England Journal of Medicine

News

1 year ago

Epidermolysis bullosa (EB), better known as butterfly baby disease, is a genetic disorder that involves the continuous formation of bullous lesions on the skin, due to very small mechanical trauma…

Hologene 5: A Phase II/III Clinical Trial of Combined Cell and Gene Therapy of Junctional Epidermolysis Bullosa

Publications

1 year ago

De Rosa L, Enzo E, Zardi G, Bodemer C, Magnoni C, Schneider H, De Luca M. ABSTRACT Epidermolysis bullosa (EB) is a group of devastating genetic diseases characterized by skin…

The main aim of Holostem Terapie Avanzate is to promote epithelial stem cell-based Regenerative Medicine for patients with no alternative therapeutic solutions.